Causes of prostatitis

• Infections (sexually transmitted diseases, other potential foci of infection) infection is the most common and probable cause of chronic prostatitis. Even in 1909, Holtz BN argued that prostatitis often is a complication of gonorrheal infection and prostate health in chronic gonorrhea - exception. In this era of doantibiotikovuyu the opinion of many scholars, but in recent decades due to widespread use of antibiotics, the proportion of gonorrheal urethritis in relation to negonokokkovym markedly decreased. The most common acute and chronic bacterial prostatitis caused by gram-flora and, particularly, E. coli, which accounted for 80% of all cases
• Factors contributing to the development of prostate blood circulation disturbances, stagnation and congestion; There are descriptions of prostate inflammation associated with persistent congestion in the veins of the pelvis, resulting in a breach of drainage prostate acini (kongenstivnye prostate), with metabolic disorders. Found that patients with chronic prostatitis recorded various changes of microcirculation, hemocoagulation and fibrinolysis. It is axiomatic that the congestion of the prostate gland predispose to its inflammation. Among the reasons contributing to congestion is called sexual violation and dysrhythmia sexuality. Leader A. J. (1958) argued: "The root cause of vesicle-prostate are repeated sexual arousal without physiological emptying a secret.

• Long-term abstinence, leading to a delay of secretion in the prostate gland, may be the cause of its aseptic inflammation.

• Neurogenic dysfunction of the pelvic floor muscles (hypertonicity, often in combination with dissinergiey reflex-forming apparatus of the urinary bladder, hypotension);

• Violation of the barrier function of the prostate gland, is well known that the prostate gland performs barrier function, and its secret has antimicrobial action, preventing infection in the upper genital tract. Barrier function of the prostate is associated with the content in the zinc. Zinc has an antibacterial effect in vitro on grampozitivnye and gramnegativnye bacteria. It is known that most prostate is rich in zinc, zinc accumulates, and its antibacterial activity associated with the presence in it of free zinc. In addition, the gland is formed zinc-peptide complex, which plays the role of prostatic antibacterial factor (Stamey 1968, Marmar 1975, Fair & Wehner 1976, Fair & Parrish 1981). It was shown that the penetration of bacteria in the prostate, the primary defect is its inability to accumulate zinc. In bacterial prostatitis and reduced zinc levels did not change after oral administration of drugs Zn. In contrast, when abakterialnom prostate zinc levels restored at his admission (Stamey 1968, Marmar 1975, Kavanagh JP 1982). Other factors, providing a barrier function body are: factors of cellular immunity (macrophages, etc.) and immunoglobulins IgA, IgG, IgM, which are produced in the prostate or prostatic penetrate the barrier in the seminal fluid, lysozyme, spermine, PH Secret - 6,6 . In inflammation the pH rises to 7-8 (Fowler J. 1988, Shortliffe LMD1981). Against the background of chronic prostatitis showed statistically significant reduction in citric acid.

• Hormonal imbalances;

• Violations of immunity (immunodeficiency, autoimmune process), allergic status (infectious-allergic or allergic process), factors contributing to the emergence and development of chronic prostatitis may be immune disorders and allergic status change. Some authors support the view that the emergence of nebakterialnogo prostatitis caused by immunologic processes, accelerated unknown antigen or an autoimmune reaction (Shortliffe LM, Wehner N., 1986, Doble A. et al., 1990, Nickel JC et al., 1990). The development of inflammation in the prostate causes changes in the microcirculation, resulting in increased vascular permeability, causes an opportunity of release of serum proteins into the surrounding tissues and even the secret of the prostate gland. Depending on the state histohematogenous barerovpredstatelnoy gland in various forms of chronic prostatitis in secret may appear larger or smaller quantities of blood serum protein fractions with different molecular weight that allows you to indirectly judge the transkapillyarnom exchange membrane structures and state authority. With long-term course of the disease may cause sensitization of the organism tissues of the prostate, entailing allergy organism, both local and general nature. The emergence of delayed-type inflammatory responses to live pathogens - microorganisms and their toxins associated with the direct influence of the agent and the decay products of body tissue. Later persistent inflammation in the prostate gland can be maintained by autoimmune mechanisms.
• Deficiency of vitamins and trace elements;

• psychosomatic disorders.
Rx Tennessee